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Updated on September 14, 2022 in Marketplace
0 on September 14, 2022

Codeine is an opiate useful in the treatment of pain, cough, and diarrhea. Codeine is a naturally occurring drug that makes up about 2% of opium. It acquires its place on the World Health Organization’s List of Essential Medicines, which consists of the safest and most essential medicines required in a health system. Codeine is one of the most commonly taken opioids around the world.

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Codeine pills contain codeine sulfate, an opioid, generally in the strength of 15mg, 30mg, or 60mg. People buy codeine online for treating mild to an average level of pain. However, it is much more effective as a combinational medication when combined with acetaminophen (paracetamol) or non-steroidal anti-inflammatory drugs (NSAID) such as ibuprofen or aspirin. It is also helpful as a cough suppressant for adults.

Codeine half-life

Codeine drug typically starts working after half an hour and reaches its peak effects in about two hours. The codeine effects last for four to six hours in an average adult.

Codeine half-life is about 2.9 hours in plasma. However, the drug primarily eliminates via kidneys. About 90% of the total oral dose excreted by kidneys within 24 hours of intake.

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Codeine pills are for use in patients who do not get adequate pain relief through other treatment options such as non-opioid or other opioid analgesics. Doctors should adjust the dosage schedule for each patient individually based upon the patient’s previous analgesic experiences.

The usual dosage for adults is 15mg to 60mg given every four hours as needed. A maximum 24-hour dose for analgesia is 360mg.

Titrate the dose to get an acceptable level of analgesia, keeping in mind the patient’s tolerance for the drug. Tolerance to codeine pills can develop with higher doses or continued use.

Gradually reduce the doses when a patient no longer requires therapy to prevent symptoms of withdrawal.


Codeine effects

The adverse codeine effects include:

    • Respiratory or circulatory depression
    • Cardiac arrest
    • Allergic reactions
    • Euphoria or sedation
    • Abdominal distress
    • Palpitations
    • Hypotension
    • Anorexia
    • Gastrointestinal distress

Codeine for cough

Codeine is an opioid and an antitussive. People use codeine for cough suppression. Codeine decreases the activity of a cough-causing part of the brain. It is an opioid cough suppressant not recommendable for children under 18 years of age due to dependence and addiction factors associated with opioids. It is highly recommended not to use codeine for a cough caused due to the common cold and flu.

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Codeine cough syrup dosage

Take codeine cough syrup dosage as prescribed by the doctor. Consume the cough syrup with enough water, with or without food. A doctor sets the dosage according to the medical condition and response of an individual patient.

Codeine combinations

Codeine drug comes in combination with acetaminophen and other drugs. Different combination medications are useful for different medical conditions. Tylenol with codeine is a combination medication available in both tablet and oral solution formulation.


Tylenol with codeine dosage forms and strengths include:

Tablets (Schedule III)

Codeine 15mg/ 300mg

Codeine 30mg/300mg

Codeine 60mg/300mg

How to get Codeine?

You can buy codeine online or from nearby pharmacies and drug stores. Always buy medicines from government-approved pharmacies to avoid the chances of getting fake medication.

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