What Is Dilaudid?
Dilaudid (hydromorphone hydrochloride) and Dilaudid Injection (also termed Dilaudid HP) are the tablet, liquid and IV forms of an opioid analgesic used for control of moderate to severe pain. Dilaudid is available in generic form.

This medication is used to help relieve moderate to severe pain. Hydromorphone belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain.
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How to use Dilaudid
Before beginning to use hydromorphone and each time you get a refill, read the Medication Guide that your pharmacist has provided. Ask your physician or pharmacist if you have any inquiries.
As prescribed by your doctor, take this medication by mouth. This medication can be used with or without food. Taking this medication with food may help if you experience nausea. Consult your physician or pharmacist about additional methods of reducing nausea.
The dosage is based on your medical condition and response to treatment. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed.
It is recommended to take painkillers as soon as the first signals of pain appear. The drug might not function as well if you wait until the pain has gotten worse.
If you have used this drug often or in high dosages, stopping it suddenly may result in withdrawal symptoms. Your doctor might gradually reduce your dose to prevent withdrawal. If you have any withdrawal symptoms, such as restlessness, mental/mood problems (such as anxiety, difficulties sleeping, or suicidal thoughts), watering eyes, runny nose, nausea, diarrhea, sweating, muscular aches, or abrupt changes in behavior, call your doctor or pharmacist straight away.
Long-term usage of this drug may cause it to lose some of its effectiveness. If this drug stops working as well, consult your doctor.
What Are Side Effects of Dilaudid?
Common side effects of Dilaudid include
- flushing (warmth,
- redness, or tingling of skin),
- itching,
- sweating,
- nausea,
- vomiting,
- constipation,
- diarrhea,
- stomach pain,
- dizziness,
- drowsiness,
- blurred vision,
- double vision,
- headache,
- sleep problems (insomnia),
- strange dreams, and
- dry mouth.
Dilaudid dosage
Dilaudid is sold as an injection that contains 1, 2, or 4 mg of hydromorphone hydrochloride together with 0.2% sodium citrate and 0.2% citric acid solution. It is also sold as tablets with an 8 mg strength, liquid with a 5 mg strength per 5 ml of liquid, and in tablet form with an 8 mg strength. Tablet dosage typically starts at 2-4 mg every 4-6 hours, while liquid dosage starts at 2.5 mg (2.5 ml) every 3-6 hours and can be adjusted based on the patient’s response and the physician’s prescription. The initial dose of dilaudid injection is 1-2 mg either subcutaneously or intramuscularly every 4 to 6 hours as needed for pain; it may also be administered intravenously (IV) slowly over 2-3 minutes, but respiration must be watched.
What Medicines, Drug Products, or Dietary Supplements Interact with Dilaudid?
Buprenorphine, butorphanol, nalbuphine, pentazocine, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bladder or urinary medicines, bronchodilators, irritable bowel syndrome medications, or ulcer medications are some of the drugs that buprenorphine may interact with. Other narcotic painkillers, sedatives, tranquilizers, Give your doctor a complete list of all the drugs and supplements you take.
Additional Information
Our Dilaudid and Dilaudid Injection Side Effects Drug Center offers an in-depth look at the various drug information sources regarding the possible side effects of taking this medication.
There may be additional adverse effects; this is not a comprehensive list. For medical advice about side effects, contact your doctor. Call 1-800-FDA-1088 to report side effects to the FDA.
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